General Cell Based Assays
Cayman Chemical GGT Substrate 1ea
GGT substrate has been tested and formulated to work exclusively with Cayman’s γ-Glutamyl Transferase Activity Assay Kit (Item No. 702210).
Cayman Chemical Phosphatidylcholine Colorimet
Cayman’s PC Assay provides a specific, sensitive, and convenient method for quantifying PC in plasma or serum. In this assay, PC-Specific PLD hydrolyzes PC to choline and phosphatidic acid. The newly formed choline is then used to generate hydrogen peroxide in a reaction catalyzed by choline oxidase. Finally, with peroxidase as a catalyst, hydrogen peroxide reacts with DAOS and 4-aminoantipyrine to generate a blue dye with an optimal absorption at 595 nm.
Eurofins Discoverx PathHunter Human CHRM2 Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human CHRM2 Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure CHRM2 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human OPRD1 (Opioid Delta) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human OPRD1 (Opioid Delta) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure OPRD1 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Mouse OPRM1 (Opioid mu) β-Arrestin Cell-Based Assay Kit (U2OS)
The PathHunter Mouse OPRM1 (Opioid mu) β-Arrestin Stable Cell Line Assay (U2OS) contains a stable clonal cell line used to measure mOPRM1 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human LPA3 (EDG7) Activated GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human LPA3 (EDG7) Stable Cell Line Activated GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure EDG7 (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human Calcitonin (CALCR (No RAMP)) β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human Calcitonin (CALCR (No RAMP)) β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure CALCR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human FXR Nuclear Receptor Protein Interaction Cell-Based Assay Kit (CHO-K1)
The PathHunter Human FXR Nuclear Receptor Stable Cell Line Protein Interaction Assay (CHO-K1) contains a stable clonal cell line used to measure activated FXR nuclear hormone receptor interaction with SRCPs. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human NMU1R Total GPCR Internalization Cell-Based Assay Kit (U2OS)
The PathHunter Human NMU1R Stable Cell Line Total GPCR Internalization Assay (U2OS) contains a stable clonal cell line used to measure NMU1R (GPCR) internalization via early-endosome localization. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Revvity Health Sciences Inc HTRF cAMP Gi Detection Kit, 20,000 Assay Points
HTRF cAMP Gi Detection Kit, 20,000 Assay Points
Revvity Health Sciences Inc HTRF Human Phospho-BAD (Ser112) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-BAD (Ser112) Detection Kit, 50,000 Assay Points
Revvity Health Sciences Inc HTRF Tau Aggregation Kit, 500 Assay Points
HTRF Tau Aggregation Kit, 500 Assay Points
Cytoskeleton, Inc. ACTIN POLYMRIZATION BIOCHM KIT
Actin Polymerization Kit (Fluorescence format) - Cytoskeleton, Inc.
Cayman Chemical FFAR4GPR120 Reporter asy 1ea
An IRE1a inhibitor (IC50s 0.2 and 0.02 UM for RNase and kinase activity respectively) selective for IRE1a over Ron and FGFR1 (IC50s 4.4 and 17 UM) as well as a panel of 282 kinases at 10 UM inhibits ER stress-induced increases in the splicing of mRNA encoding XBP1 in eight multiple myeloma cell lines at 8 UM reduces viral replication in tick-borne encephalitis virus-infected SH-SY5Y and SNB-19 cells at 0.5 UM and tick-borne encephalitis virus-infected Caco-2 cells at 1 UM
Cayman Chemical GlutathIon Reductase asy K 96
GR is a flavoprotein that catalyzes the NADPH-dependent reduction of oxidized GSSG to GSH. This enzyme is essential for the GSH redox cycle which maintains adequate levels of reduced cellular GSH. A high GSH/GSSG ratio is essential for protection against oxidative stress. Cayman’s Glutathione Reductase Assay Kit measures GR activity by measuring the rate of NADPH oxidation. The oxidation of NADPH to NADP+ is accompanied by a decrease in absorbance at 340 nm. The rate of decrease in the absorbance at 340 nm is directly proportional to the GR activity in the sample.